Assistant Professor


Curriculum vitae



Department of Obstetrics and Gynecology

Department of Health Research Methods, Evidence and Impact

McMaster University
1280 Main St. West,
HSC3V - 43B
Hamilton, Ontario ​L8S 4K1
Canada



Does Maternal Stature Modify the Association Between Small- and Large-For-Gestational Age Infants and Adverse Perinatal Outcomes? A Retrospective Cohort Study.


Journal article


Lauren M. Yearwood, J. Bone, Qi Wen, G. Muraca, Janet Lyons, N. Razaz, K. Joseph, S. Lisonkova
BJOG: an International Journal of Obstetrics and Gynaecology, 2022

Semantic Scholar DOI PubMed
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APA   Click to copy
Yearwood, L. M., Bone, J., Wen, Q., Muraca, G., Lyons, J., Razaz, N., … Lisonkova, S. (2022). Does Maternal Stature Modify the Association Between Small- and Large-For-Gestational Age Infants and Adverse Perinatal Outcomes? A Retrospective Cohort Study. BJOG: an International Journal of Obstetrics and Gynaecology.


Chicago/Turabian   Click to copy
Yearwood, Lauren M., J. Bone, Qi Wen, G. Muraca, Janet Lyons, N. Razaz, K. Joseph, and S. Lisonkova. “Does Maternal Stature Modify the Association Between Small- and Large-For-Gestational Age Infants and Adverse Perinatal Outcomes? A Retrospective Cohort Study.” BJOG: an International Journal of Obstetrics and Gynaecology (2022).


MLA   Click to copy
Yearwood, Lauren M., et al. “Does Maternal Stature Modify the Association Between Small- and Large-For-Gestational Age Infants and Adverse Perinatal Outcomes? A Retrospective Cohort Study.” BJOG: an International Journal of Obstetrics and Gynaecology, 2022.


BibTeX   Click to copy

@article{lauren2022a,
  title = {Does Maternal Stature Modify the Association Between Small- and Large-For-Gestational Age Infants and Adverse Perinatal Outcomes? A Retrospective Cohort Study.},
  year = {2022},
  journal = {BJOG: an International Journal of Obstetrics and Gynaecology},
  author = {Yearwood, Lauren M. and Bone, J. and Wen, Qi and Muraca, G. and Lyons, Janet and Razaz, N. and Joseph, K. and Lisonkova, S.}
}

Abstract

OBJECTIVE To investigate the effect of maternal stature on adverse birth outcomes and quantify perinatal risks associated with small- and large-for-gestational age infants (SGA and LGA, respectively) born to mothers of short, average, and tall stature.

DESIGN Retrospective cohort study.

SETTING USA, 2016-2017.

POPULATION Women with a singleton live birth (N=7 325 741).

METHODS Using data from the National Center for Health Statistics, short and tall stature were defined as <10th and >90th centile of the maternal height distribution. Modified Poisson regression was used to estimate adjusted risk ratios (ARR) and 95% confidence intervals (CI).

MAIN OUTCOME MEASURES Preterm birth (<37 weeks' gestation), neonatal intensive care unit (NICU) admission, and severe neonatal morbidity/mortality (SNMM).

RESULTS With increased maternal height, risk of adverse outcomes increased in SGA infants and decreased in LGA infants compared with appropriate-for-gestational age (AGA) infants (p<0.001). SGA infants of tall women had the highest risk of NICU admission (ARR 1.98, CI: 1.91-2.05; p<0.001), while LGA infants of tall women had the lowest risk (ARR 0.85, CI 0.82-0.88; p<0.001) compared with AGA infants of average statured women. LGA infants of short statured women had an increased risk of NICU admission and SNMM compared with AGA infants of average statured women (ARR 1.32, CI 1.27-1.38; ARR 1.21, CI 1.13-1.29, respectively).

CONCLUSION Maternal height modifies the association between SGA and LGA status at birth and neonatal outcomes. This quantification of risk can assist healthcare providers in monitoring fetal growth, and optimizing neonatal care, and follow up.


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