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Associate Professor


Department of Obstetrics and Gynecology

Department of Health Research Methods, Evidence and Impact

McMaster University
1280 Main St. West,
HSC3V - 43B
Hamilton, Ontario ​L8S 4K1
Canada



Severe maternal and neonatal morbidity or mortality in forceps versus cesarean birth in the second stage of labor: A systematic review and meta-analysis


Journal article


Irina I. Oltean, Abirami Kirubarajan, Giulia M. Muraca
Int J Gynaecol Obstet, 2026


Semantic Scholar DOI PubMed
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APA   Click to copy
Oltean, I. I., Kirubarajan, A., & Muraca, G. M. (2026). Severe maternal and neonatal morbidity or mortality in forceps versus cesarean birth in the second stage of labor: A systematic review and meta-analysis. Int J Gynaecol Obstet. https://doi.org/10.1002/ijgo.71152


Chicago/Turabian   Click to copy
Oltean, Irina I., Abirami Kirubarajan, and Giulia M. Muraca. “Severe Maternal and Neonatal Morbidity or Mortality in Forceps versus Cesarean Birth in the Second Stage of Labor: A Systematic Review and Meta-Analysis.” Int J Gynaecol Obstet (2026).


MLA   Click to copy
Oltean, Irina I., et al. “Severe Maternal and Neonatal Morbidity or Mortality in Forceps versus Cesarean Birth in the Second Stage of Labor: A Systematic Review and Meta-Analysis.” Int J Gynaecol Obstet, 2026, doi:10.1002/ijgo.71152.


BibTeX   Click to copy

@article{irina2026a,
  title = {Severe maternal and neonatal morbidity or mortality in forceps versus cesarean birth in the second stage of labor: A systematic review and meta-analysis},
  year = {2026},
  journal = {Int J Gynaecol Obstet},
  doi = {10.1002/ijgo.71152},
  author = {Oltean, Irina I. and Kirubarajan, Abirami and Muraca, Giulia M.}
}

Abstract

BACKGROUND Approximately one in four first-time mothers reach the second stage of labor but cannot have a spontaneous vaginal birth, necessitating an intervention such as forceps to facilitate birth.

OBJECTIVE This study synthesizes evidence comparing severe maternal morbidity (SMM) and neonatal morbidity or mortality (SNMM) following forceps and cesarean birth (CB) in the second stage of labor.

METHOD Four databases were searched from database inception to May 30, 2023. Original studies comparing SMM or SNMM among individuals with an attempted forceps birth versus second stage CB were included. Meta-analyses were conducted using the Mantel-Haenszel random-effects model and the risk ratio (RR) was used as an effect measure with 95% confidence intervals (CIs).

RESULTS After screening 945 articles, a total of 13 cohort studies encompassing 52 192 individuals were included. Four studies with 34 131 total individuals provided data on SMM. The incidence of SMM was 2.6% with attempted forceps versus 3.7% with second-stage CB (pooled RR of 0.83, 95% CI 0.64, 1.07). Six studies with a total of 36 135 individuals provided data on SNMM. The incidence of SNMM was 4.5% with forceps versus 2.1% with second stage CB (pooled RR of 1.34, 95% CI 0.90, 2.00). The evidence is very uncertain about the effect of attempted forceps on SMM and SNMM due to moderate or serious risk of bias, inconsistency, and heterogeneity.

CONCLUSION Risks of SMM and SNMM are unclear after forceps and second stage CB and the choice between operative interventions should depend on the clinical scenario. Our study protocol was registered in the International Prospective Register of Systematic Reviews (PROSPERO) database (CRD42023387112) on January 2, 2023.



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